IndraLab

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P14_3_3 inhibits USP8. 3 / 5
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reach
"Another hypothesis is that USP8 is catalytically inhibited in a phosphorylation dependent manner by 14-3-3 proteins during the interphase stage of the cell-cycle, and this regulation is reversed in the M phase [XREF_BIBR]."

sparser
"Another hypothesis is that USP8 is catalytically inhibited in a phosphorylation-dependent manner by 14-3-3 proteins during the interphase stage of the cell-cycle, and this regulation is reversed in the M phase [ xref ]."

sparser
"We conclude that UBPY is catalytically inhibited in a phosphorylation-dependent manner by 14-3-3s during the interphase, and this regulation is cancelled in the M phase."