IndraLab

Statements

EIF3H inhibits MYC. 4 / 4
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"Overexpression of eIF3h has recently been shown to inhibit Myc dependent induction of apoptosis of primary prostate cells and EIF3H and MYC and may cooperate in enhanced protein translation either in a general way or for a specific subset of mRNAs XREF_BIBR."
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"XREF_BIBR Coamplification of EIF3H may also reduce MYC dependent apoptosis in prostate epithelial cells."
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"Furthermore, overexpressed eIF3h inhibits Myc dependent induction of apoptosis of primary prostate cells."
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"However, it was recently reported that overexpression of EIF3H inhibited Myc dependent induction of apoptosis in primary prostate cells, which suggests that EIF3H and MYC may cooperate to enhance protein translation [38]."
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