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OTUD1 binds AIFM1. 15 / 15
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sparser
"We next performed in vitro pulldown assays to investigate whether OTUD1 could directly bind to AIF."
33898171
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"As described above, OTUD1 binds and regulates the mitochondrial antiapoptotic protein AIF, and this interaction is associated with caspase-dependent apoptosis and caspase-independent parthanatos with OXPHOS-related ROS production ( xref C) [ xref ]."
36829909
sparser
"Co‐IP assays showed that AIF selectively binds to the linker domain of OTUD1 (Figure S3C, Supporting Information), while OTUD1 associates with the NADH binding and Loop domains of AIF (Figure S3D, Supporting Information)."
33898171
biogrid
No evidence text available
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No evidence text available
36929488
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No evidence text available
35941131
reach
"As described above, OTUD1 binds and regulates the mitochondrial antiapoptotic protein AIF, and this interaction is associated with caspase-dependent apoptosis and caspase-independent parthanatos with OXPHOS-related ROS production (Figure 3C) [36]."
36829909
biogrid
No evidence text available
33898171
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No evidence text available
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No evidence text available
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"The study reveals that OTUD1 binds directly to AIF and mediates the deubiquitination of AIF lysine sites 244 and 255, thereby triggering caspase-independent apoptosis."
35874820
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No evidence text available
33898171
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No evidence text available
33898171
sparser
"OTUD1 Interacts with AIF and Promotes AIF Nuclear Translocation."
33898171
sparser
"Among the proteins identified by MS, we focused on AIF (Figure  xref , xref ), which functions as an inducer of the caspase‐independent apoptosis pathway. [ xref ] To validate the interaction between OTUD1 and AIF, we first cotransfected Flag‐AIF and V5‐OTUD1 into 293T cells and performed immunoprecipitation using anti‐Flag magnetic beads."
33898171