IndraLab

Statements

PSMD14 activates cell population proliferation. 13 / 13
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"Knockdown and overexpression experiments elucidated that PSMD14 stimulated OV cell proliferation, invasion and migration in vitro."
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"The knockdown of POH1 significantly inhibited tumor cell proliferation and induced apoptosis mediated by the mitochondrial pathway in vitro."
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"POH1 depletion, for example, has been shown to impair multiple myeloma cell proliferation [190]."
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"Recent studies have demonstrated that p53 is involved in PSMD14 mediated cell proliferation; p53 is upregulated in PSMD14-knockdown cells, and knockdown of PSMD14 induces cancer cell apoptosis mediated via p53 XREF_BIBR."
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"PSMD14 knockdown notably inhibited cell proliferation, migration, and invasion in vitro, which was confirmed through in vivo experiments."
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"Gain and loss of function experiments demonstrated that PSMD14 deficiency inhibited bladder cancer cell proliferation."
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"PSMD14 knockdown notably inhibited cell proliferation , migration , and invasion in vitro , which was confirmed through in vivo experiments ."
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"Depletion of PSMD14 suppresses bladder cancer proliferation by regulating GPX4."
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"Depletion of PSMD14 could inhibit the proliferation of bladder cancer cells through the downregulation of GPX4."
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"PSMD14 overexpression was found to promote the proliferation, invasion, migration of HTR-8/SVneo cells and the angiogenesis of HUVECs following treatment with the HTR-8/SVneo cell culture supernatant, accompanied by enhanced expression of proliferation and migration-related proteins."
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"The colony formation assay confirmed that POH1 silencing reduced cell proliferation in HCC, EC, and CRC, as the number of colonies formed by POH1 silenced cells was much lower than that in the control groups (XREF_FIG C)."
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"MTT and colony formation assays revealed that the overexpression of POH1 failed to promote cell proliferation (XREF_FIG E-F)."
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"In conclusion, HEY1-activated PSMD14 promoted trophoblast proliferation, invasion and angiogenesis."
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