IndraLab

Statements

RAET1E binds KLRK1. 4 / 8
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"ULBP4-NKG2D interaction can not only activate NK cell and NK-mediated cytotoxicity [ xref , xref , xref ], but also serve to stimulate the cytotoxicity of CD8+ T cell [ xref ], which suggests an influence of ULBP4 on both innate and adaptive immune responses."
28159927
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"In addition, the receptor–ligand analysis using the CellPhoneDB database illustrated that the strength of the interaction between NKG2DLs, including MICB (Micb) and RAET1E (Raet1e), of NP cells and the NKG2D of the identified other cells, was increased at 8 w post‐puncture (Figure 2G)."
38554394
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"RAET1E binds and activates NKG2D-expressing NK and CD8 T cells, with RAET family members typically absent on normal cells but overexpressed under stress."
39994453
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"It is intriguing that ULBP-4 and hMSH2 can also bind to NKG2D to induce the cytotoxicity of Vgamma9Vdelta2-T cells against tumor cells through TCR and NKG2D engagement."
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