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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Mutated CYLD activates Neoplasms. 2 / 2

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"A benign tumor syndrome of hair follicles known as cylindromatosis is caused by the mutation of CYLD, a USPfamily DUB named after the disease it causes."

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"Since it is been well-known that CYLD mutation in humans causes several types of skin tumors and CYLD also has an anti-inflammatory function in IBD patients, our findings suggest that CYLD may regulate immune tolerance by regulating Treg function in humans."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...