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HMGCR activates BRCC3. 1 / 1
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"We found that overexpression of HMGCR or mutant HMGCR significantly abrogated the tumor growth suppression in BRCC36‐knockout tumors, indicating that the oncogenic effect of BRCC36 is dependent on HMGCR (Figure 6K,L; Figure S6I–K, Supporting Information)."