IndraLab

Statements


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"These data suggest that delayed oseltamivir plus sirolimus treatment reduces NLRP3 inflammasome activity, which is correlated with downregulated NF-κB activity and ROS production, and induced autophagy after pH1N1 infection."

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"In an experimental animal model of H1N1 influenza, rapamycin in combin ation with oseltamivir reduced viral replication and the NLRP3 inflammasome."

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"Delayed oseltamivir and sirolimus combined treatment could suppress NLRP3 inflammasome mediated secretion of IL-1beta and IL-18, resulting in attenuation of H1N1 induced lung injury [XREF_BIBR]."