IndraLab

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"Also, we show that, while amiodarone inhibits the Cole-Moore shift, dronedarone is unable to inhibit this voltage dependent characteristic of Kv10.1."

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"The latter supports previous observations showing that dronedarone, a related and also less hydrophobic molecule than Ad, in this case due to the addition of a hydrophilic group, is similarly unable to inhibit the Kv10.1 Cole-Moore shift [15]."