IndraLab

Statements



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"Therefore, Cyclosporine A and FK506, immunosuppressive compounds, which are calcineurin inhibitors widely used as immunosuppressors in the clinic, prevent TRESK activation."

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"In the present study, we found that the selective calcineurin inhibitor FK506 prevented TRESK activation in HEK293 cells."

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"Cyclosporin A and FK506, specific inhibitors of the calcium/calmodulin dependent protein phosphatase (calcineurin), completely eliminated TRESK activation."