IndraLab

Statements

USP7 inhibits E3_Ub_ligase. 5 / 5
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"Next, the E3 ubiquitin ligase activity of UHRF1 is hypothesized to be directly decreased by USP7."
35005106
eidos
"Next , the E3 ubiquitin ligase activity of UHRF1 is hypothesized to be directly decreased by USP7 ."
35005106
reach
"Second, we hypothesize that HAUSP directly inhibits the E3 ubiquitin ligase activity of UHRF1."
21045206
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"Indeed, HAUSP was shown to reduce the E3 ligase activity (autoubiquitination) of wild-type UHRF1 but not in the UHRF1 K659E mutant, disturbing the UHRF1 domain involved in its interaction with HAUSP [XREF_BIBR]."
27839516
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"Depletion of USP7 impairs mitotic progression, stabilizes cyclin B and reduces stability of the mitotic E3 Ub ligase, checkpoint with forkhead and Ring-finger (CHFR)."
23348568