IndraLab

Statements

TRAF3 binds OTUD5. 13 / 14
2 1 | 4 6
sparser
"DUBA not only interacts with TRAF3 and inhibits TRAF3 ubiquitination, but also interrupts the interaction between TRAF3 and TBK1."
32850399
reach
"DUBA interacts with and de-ubiquitinates TRAF3, thereby attenuating TLR dependent and TLR independent antiviral responses XREF_BIBR."
21625535
reach
"DUBA directly binds tumor necrosis factor receptor-associate factor 3 (TRAF3) and cleaves its K63linked polyubiquitin chains, and its expression is suppressed during IL-1R1 stimulation [30] ."
| PMC
reach
"The interaction between DUBA and TRAF3 occurs during TLR3 activation [197]."
| DOI
biogrid
No evidence text available
17991829
sparser
"The interaction between DUBA and TRAF3 occurs during TLR3 activation [197] ."
| DOI
sparser
"Interference with the Lys63-linked auto-ubiquitination of TRAF3 is performed by DUBA (OTUD5), which interacts with TRAF3 [50]."
28625850
reach
"Interestingly, DUBA physically interacts with TRAF3 and inhibits the self ubiquitylation of TRAF3 (XREF_FIG)."
18535581
sparser
"An unambiguous identification of DUBA-interacting proteins suggests that DUBA interacts with TRAF3, whose K63-linked polyubiquitination is required for TLR-and RLR-mediated signaling."
32215003
sparser
"Fig. 4 shows the TRAF3-DUBA interaction model that we obtained by PRISM [36], [37], [38], in which the concave crevice on TRAF-C of TRAF3 is in contact with DUBA."
27208423
hprd
No evidence text available
17991829
sparser
"Interestingly, DUBA physically interacts with TRAF3 and inhibits the self-ubiquitylation of TRAF3 (Ref. xref ) ( xref )."
18535581
biogrid
No evidence text available
24763515