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USP47 inhibits ISRE. 2 / 2

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"Overexpression of USP47 reduced SeV-induced ISRE and IFN-β reporter activation in a dose-dependent manner in HEK293T cells ( Fig. 1 A, B)."

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"In addition, USP47 suppressed RNA virus mimics poly (I:C), and DNA virus mimics poly(dA:dT)- induced ISRE and IFN-β activation ( Fig. 1 C-F), establishing the negative regulatory role of USP47 in anti[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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IndraLab

Statements

USP47 inhibits ISRE. 2 / 2

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