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"Our results showed that USP13 short hairpin RNA inhibited ZHX2 expression and ccRCC cell growth, while these changes were rescued by the USP13 cDNA (short hairpin RNAs resistant) (SI Appendix, Fig. S4C and Fig. 3 D–G), revealing that the effect of USP13 short hairpin RNA on ZHX2 and soft agar growth was on-target."