IndraLab

Statements


PKCepsilon isoenzymes leads to the phosphorylation of KCNQ1. 2 / 2
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"By phosphorylating distinct sites in KCNQ1 and KCNE1, cPKC and PKCepsilon isoenzymes produce contrary regulatory effects on the channel."

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"Our results demonstrate that PKCepsilon isoenzyme mediates the inhibitory action of Ang II on I Ks and by phosphorylating distinct sites in KCNQ1 and KCNE1, cPKC and PKCepsilon isoenzymes produce the contrary regulatory effects on the channel."