IndraLab

Statements


OTUB2 activates TNBC. 4 / 4
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"The results demonstrated that OTUB2 knockdown significantly inhibited TNBC cell growth, while overexpression promoted cell growth in a time-dependent manner (Fig. 3A,B)."

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"Additionally, while our findings suggest that OTUB2 promotes TNBC cell migration, this conclusion is based solely on in vitro assays, and we lack in vivo metastasis models to further validate its role in tumor dissemination."

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"OTUB2 promotes TNBC cell proliferation in vitro and tumor growth."

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"Furthermore, overexpression of OTUB2 promoted TNBC cell proliferation and migration, whereas silencing of OTUB2 resulted in the opposite effect."