IndraLab

Statements

Desferrioxamine B inhibits RELA. 2 / 2
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"51 In our study, we found that DFO could downregulate ERK, JNK, p38 and p65 activation in osteoclast differentiation, evidenced by little ERK, JNK, p38 and p65 phosphorylation after DFO treatment."
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"Specifically, treatment with DFO decreased the transcript counts of mammalian target of rapamycin (mTOR; p=0.002, Figure 5I), nuclear factor kappa B p65 (NF-κB p65; p=0.0004, Figure 5J), and the gene coding for cyclooxygenase-2: prostaglandin-endoperoxide synthase 2 (PTGS-2; p=0.007, Figure 5K)."
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