IndraLab

Statements


USP9X deubiquitinates MAP3K5. 3 / 4
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"USP9X also promoted apoptosis in HCC by deubiquitinating apoptotic signaling-regulating kinase (ASK1) and enhancing oxidative stress-induced JNK activation and cell death [70]."

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"USP9X binds with and deubiquitinates ASK1, advancing the ASK1-p38/JNK pathway under oxidative stress conditions [115]."

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"It has been reported that USP9X can deubiquitinate and stabilize ASK1 and ZBTB38 and therefore, antagonize the OSS damage [ 14 , 15 ]."