IndraLab

Statements

IL6 increases the amount of COPS5. 3 / 3
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"We also analyzed whether the siRNA mediated inactivation of Stat3 and Src could reduce Jab1-promoter activity and whether interleukine-6 (IL-6) could mediate increased Jab1 expression through Stat3 signaling."
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"We further investigated whether an upstream activator of Stat3, the cytokine IL-6, could be driving increased Jab1 expression."
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"Taken together, it is evident that both IL-6 and Src signaling through Stat3 is contributing to Jab1 transcription and increased expression in breast cancer."
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