IndraLab

Statements

BRCC3 activates temozolomide. 4 / 4
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"BRCC3 gene knockdown through lentivirus mediated gene knockdown approach not only significantly reduced the clonogenic and migratory abilities of U251 and A172 cells, but also enhanced their sensitization to TMZ."
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"BRCC3 led to the resistance of glioma cells to temozolomide (22)."
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"Accordingly, we examined if the depletion of BRCC3 promotes TMZ induced cytotoxicity in U251 and A172 cells."
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"Our data showed that BRCC3 gene knockdown reduced the cell viability of TMZ treated U251 and A172 cells when compared to the relative TMZ treated mock cells."
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