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OTUD4 activates cell death. 2 / 2

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"In our study, we verified that OTUD4 silence increased airway epithelial cell apoptosis and restoration of OTUD4 attenuated the CSE induced epithelia apoptosis.Although OTUD4 modulating cell death, the molecular mechanism of OTUD4 regulated cell apoptosis is still ambiguous."

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"We further found that OTUD4 sensitized ccRCC cells to Erastin-induced ferroptosis, and ferrostain-1 inhibited OTUD4-induced ferroptotic cell death."

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OTUD4 activates cell death. 2 / 2

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