IndraLab

Statements


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"CGP 41251 and tamoxifen selectively inhibit mitogen activated protein kinase activation and c-Fos phosphoprotein induction by substance P in human astrocytoma cells."

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"PKC412 inhibits the activity of Ras and FGFR3 or c-fos in concentrations ranging from 0.01 to 50 muM, showing significant therapeutic effects [XREF_BIBR]."

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"CGP 41251 inhibits reversibly intracellular PKC activity, induction of c-fos and the corresponding activation of the mitogen activated protein kinase induced by either tumor promoting phorbol esters, platelet derived growth factor, or basic fibroblast growth factor, but not by the epidermal growth factor."