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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 inhibits Alzheimer Disease. 3 / 7

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"UCHL1 can promote the degradation of APP and BACE1 in AD ."

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"Zhang et al. reported that the overexpression of UCHL1 decreased Abeta in the uchl1-null AD mice (Zhang et al., 2012)."

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"Recent studies reported that the level of soluble UCHL1 protein is inversely proportional to the number of tangles, that UCHL1 is oxidized in AD brains and that overexpression of UCHL1 reverses cognit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...