IndraLab

Statements

OTUD5 deubiquitinates TRAF6. 2 / 2
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reach
"For example, TNFAIP3, CYLD, USP3, USP4, USP15, USP25, and OTUD5 deubiquitinate key components of the IFN production pathway, including RIG-I, TRAF2, TRAF3, TRAF6, RIP1, and TRIF (reviewed in [93,94])."
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"Given that TRAF3 may be dispensable for RIG-I signalling 92, it cannot be excluded, however, that <span class="match term0">DUBA</span> also targets other E3 ligases like TRAF2, 5 and 6."
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