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USP28 activates Wnt signaling. 2 / 2
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"To explore how USP28 might be involved in HCC development , we undertook a Gene Set Enrichment Analysis and found a significant positive correlation between USP28 expression and the expression of Wnt signaling pathway genes ( Figure 1D ) , suggesting that USP28 might contribute to Wnt signaling ."
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"Taken together , these data strongly suggest that USP28 contributes to Wnt signaling through maintaining the stability of TCF / LEF transcription factors ."
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