IndraLab

Statements

USP2 inhibits Carcinoma, Renal Cell. 7 / 7
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"Ubiquitin-specific peptidase 2-mediated inhibition of epithelial-mesenchymal transition in clear cell renal cell carcinoma cells is dependent on the nuclear factor-kappaB pathway."
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"Ubiquitin-specific peptidase 2 downregulation in clear cell renal cell carcinoma is associated with worse clinical stage and prognosis."
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"Ubiquitin-specific peptidase 2 inhibited the proliferation, migration, and invasion of clear cell renal cell carcinoma cells."
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"These data showed that overexpression of ubiquitin-specific peptidase 2 downregulates the metastatic ability of clear cell renal cell carcinoma cells."
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"Overexpression of ubiquitin-specific peptidase 2 suppressed metastasis of clear cell renal cell carcinoma cells in vivo."
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"Hence, ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition of clear cell renal cell carcinoma by downregulating the NF-κB pathway."
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"Ubiquitin-specific peptidase 2 inhibition promoted clear cell renal cell carcinoma cell proliferation, migration, and invasion."
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