IndraLab

Statements

L-prolylglycine inhibits NLRP3. 6 / 6
| 1 5
reach
"PG resisted N. caninum infection by regulating NLRP3 inflammasome pathway."
32891167
reach
"ROS inducer PG inhibited N. caninum replication by promoting NLRP3 inflammasome activation in vitro."
32891167
reach
"Proteolysis of the NLRP3 protein was not observed with heat killed Pg and inhibition of ECs protein synthesis with cycloheximide did not abolish the NLRP3 protein degradation induced by Pg infection in ATP pre-treated cells."
24583910
reach
"These results show that ROS mediated NLRP3 dependent inflammasome activation plays a key role in controlling N. caninum infection, and the PG can inhibit parasite replication in N. caninum infected PMs mainly by promoting NLRP3 inflammasome activation and other mechanism."
32891167
reach
"To further explore the role of PG induced NLRP3 inflammasome activation in inhibiting N. caninum infection in vivo, WT and Nlrp3 -/- mice were infected with N. caninum and then treated with PG."
32891167
eidos
"Pg + ATP downregulated NLRP3 , ASC , POP1 , but upregulated IL-1beta and CARD16 ."
33368813