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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PKC activates KCNQ2. 2 / 2

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"However, fusion with AKAP79 to target the reporter to the ion channel, thereby anchoring PKC close to a substrate, abolished this lag : in this configuration, PKC activation and suppression of KCNQ2 currents occurred simultaneously."

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"Application of either 8-Cl-AMPc (500 muM), an activator of PKA, or of the phorbol 12-myristate 13-acetate (PMA), an activator of PKC, did not produce variations of the KCNQ2 channel activity (data not[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...