IndraLab

Statements

USP7 inhibits POT1. 3 / 3
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"TSPYL5 Depletion Induces Specific Death of ALT Cells through USP7 Dependent Proteasomal Degradation of POT1."
31278054
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"In the absence of TSPYL5, USP7 can freely degrade POT1, triggering telomere dysfunction and inducing cell death (Fig. 3)."
35588569
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"TSPYL5 interacts with POT1 sequestered within APBs which may protect against USP7-mediated degradation of POT1."
35588569