IndraLab

Statements



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"Downregulation of CCND1 and USP28 Inhibits Proliferation and Induces Apoptosis in A549 Cells."

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"Downregulating USP28 expression can inhibit the proliferation and growth of lung cancer cells [XREF_BIBR, XREF_BIBR]."

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"Moreover, 53BP1 or USP28 deletion restored NPC proliferation and brain size without correcting the upstream centrosome defects or extended mitosis."

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"MTT assays showed that USP28 overexpression reduced cell proliferation in MDA-MB-231 and MCF7 cells, and these effects were partially reversed by transfection with miR-500a-5p mimics."

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"CCK-8 assay shows that si-CCND1 and si-USP28 significantly inhibit A549 cell proliferation compared with si-controls (XREF_FIG, E and F)."

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"Additionally, according to the study by Popov, et al., depletion of USP28 in HeLa and LS174T cells can inhibit cell growth and proliferation due to its inability to enhance c-Myc stability [XREF_BIBR]."

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"Importantly, silencing KLHL2 or USP28 overexpression not only inhibited AML cell proliferation but also sensitized AML cells to 5 '-AZA-induced apoptosis in vitro and in vivo."