IndraLab

Statements

SPP1 binds ITGB3. 7 / 8
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"Similarly, blockade of the interaction of integrin beta3 with OPN inhibited VSMC adhesion induced by OPN."
17868879
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"CD44, a gene found in the dormancy expression profile which interacts with ITGB3 and osteopontin to mediate adhesion and signalling (reviewed in [ xref ] and [ xref ]), was also upregulated at the protein level (p=0.01)."
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"It has been shown that ITGB3 and ITGAV subunits together bind to SPP1 to generate stable adhesions between the maternal-fetal interface in pigs after the initial attachment of conceptus trophoblast to the endometrial luminal epithelium XREF_BIBR, XREF_BIBR."
24505325
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"In addition, OPN binds to ITGB3 in uterine epithelial cells via changes in the cytoskeleton, thereby promoting embryo implantation [ 38 ]."
36731281
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"Moreover, evidence show that REL can interact with LYN and FCER1G genes and SPP1 can interact with ITGB3."
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"In addition, OPN binds to ITGB3 in uterine epithelial cells via changes in the cytoskeleton, thereby promoting embryo implantation [ 38 ]."
36731281
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"However, ITGB3 displayed conspicuously absent across all samples counterintuitively, hinting at a potential weak affinity between SPP1 and ITGB3, precluding the formation of stable complexes that could be precipitated."
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