IndraLab

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Sulfonylurea inhibits NLRP3. 2 / 2

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"Sulfonylurea-related compounds seem to block inflammasome activation somewhat upstream of NLRP3, but not by direct interaction with the NLRP3 protein [32] ."

26706279

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"Sulfonylurea drugs seem to specifically inhibit the triggering step of NLRP3 activation without affecting the NF-kappaB signaling related priming step or the activation of other inflammasomes XREF_BIBR, XREF_BIBR."

27508077

INDRA sources:

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IndraLab

Statements

Sulfonylurea inhibits NLRP3. 2 / 2

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