IndraLab

Statements

Lipopolysaccharide activates USP14. 4 / 4
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"Ctrl and USP14 KD THP-1 cells were treated with or without LPS for different time periods and the activation of TLR4 downstream signaling molecules was analyzed by western blotting."
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"We next found that LPS increased the deubiquitylating activity of USP14 and confirmed the inhibitory effect of IU1 on USP14 activity (XREF_FIG)."
28611184
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"Here, we provided further evidence showing that LPS increases USP14 activity."
28611184
reach
"To verify such results, Ctrl or USP14 KD THP-1 cells were treated with or without LPS and then NF-kappaB activation was assessed by using p65- or p50-DNA binding assay."
29326710