IndraLab

Statements

Piceatannol inhibits MAPK8. 2 / 2
| 2
reach
"While ERK activation is rapid and transient, peaking at 10 min, the JNK1 activation is delayed and more sustained reaching a maximum at 2 h. ERK activation was blocked by CP 118556, indicating it is regulated by a Src like kinase, while JNK1 was inhibited by piceatannol, revealing an upstream regulation by Syk."
10528214
reach
"SAPK1 and JNK1 activation was blocked by piceatannol, indicating that it is regulated by Syk kinase, whereas SAPK2 and p38 activation was inhibited by PP2, revealing an upstream regulation by Src like kinases."
11154209