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USP13 leads to the deubiquitination of MAP3K7. 1 / 1

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"USP13 interacts with TAK1, inhibits TAK1 activation by removing ubiquitination of TAK1, and subsequently inhibits the NF-κB & MAPK signaling pathway activation (Fig. 9), thereby treating NAFLD as a latent molecular target.As a DUB enzyme, USP13 regulates the de-ubiquitination of multiple substrate proteins to participate in many cellular processes, including mitochondrial energy metabolism, DNA damage, autophagy, and endoplasmic reticulum-associated degradation [35]."

39033101

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USP13 leads to the deubiquitination of MAP3K7. 1 / 1

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