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Statements

AKT binds USP8. 3 / 3
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"Meanwhile, we found a positive correlation between the phosphorylation levels of USP8 and AKT in PBMCs of anti‐MDA5‐positive patients (R 2 = 0.8823, p  = 0.0303) (Figure xref , Supporting Information), indicating the AKT‐USP8 regulatory axis occurred in patients."
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"Collectively, there may be a degenerative feedback loop of USP8-Akt ( xref ), and the Akt signaling pathway may be involved in the tumor-promoting effects of USP8 in cholangiocarcinoma."
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"Additionally, the interaction between USP8 and Akt also exhibits cancer-specific regulatory characteristics."
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