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"We found that TNF-alpha induced a dose dependent down-regulation of AQP1 expression (P < 0.01) at mRNA (XREF_FIG) and protein level (XREF_FIG) and a dramatic decrease in AQP5 gene expression level (about 80% of control) with all the used doses (P < 0.001) (XREF_FIG), paralleled by a comparable trend at protein level (XREF_FIG)."