IndraLab

Statements


USP22 deubiquitinates Parkinson Disease on L1. 2 / 2
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"56 USP22 physically interacts with the C‐terminus of the PD‐L1 protein and CSN5, a known DUB of PD‐L1, therefore deubiquitinates and stabilizes PD‐L1."

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"For instance, USP22 can enhance the deubiquitination and stabilization of PD‐L1 in cancer cells, suggesting its protumorigenic role in cancer [31]."