IndraLab

Statements


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sparser
"To determine whether USP15 regulates CBX5 ubiquitination and, thus, affects its expression, we first used an anti-CBX5 antibody to precipitate CBX5 in control and hypoxic PASMCs and found USP15 in those immune precipitates ( xref ), indicating that USP15 can bind to CBX5 in PASMCs."

sparser
"The influence of the RUNX1/USP15 axis on the PASMC function may result from USP15’s interaction with CBX5."

sparser
"USP15 bound to CBX5 and reduced CBX5 ubiquitination, thereby promoting CBX5 expression."

reach
"USP15 bound to CBX5 and reduced CBX5 ubiquitination, thereby promoting CBX5 expression."

reach
"To determine whether USP15 regulates CBX5 ubiquitination and, thus, affects its expression, we first used an anti-CBX5 antibody to precipitate CBX5 in control and hypoxic PASMCs and found USP15 in those immune precipitates (Figure 5B), indicating that USP15 can bind to CBX5 in PASMCs."