IndraLab

Statements

USP5 activates TNF. 3 / 3
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eidos
"50 USP5 , a stress granule protein , increases TNFalpha expression through the ubiquitin-proteasome pathway and regulates inflammatory response through Smurf1 ."
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reach
"Because inhibition of TNF-alpha production in RBL-2H3 cells treated with USP5 siRNA1 and USP5 siRNA2 was observed (XREF_FIG), we examined the effect of USP5 siRNA1 and USP5 siRNA2 on TNF-alpha mRNA expression."
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reach
"Taken together, our study for the first time clarified that the E3 ligase Smurf1 regulates USP5 protein stability and USP5 mediated TNF-alpha production through the ubiquitin proteasome pathway."
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