IndraLab

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USP35 decreases the amount of CXCL10. 2 / 2
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"Additionally, USP35 knockdown enhanced the expression of IFN-β, CXCL10, and ISG15 triggered by RNA viruses or exogenous RNA-3pRNA."

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"We used 3pRNA to activate RIGI/MAVS signaling and found that the mRNA expression level of IFNβ, CXCL10, and ISG15 was significantly enhanced by USP35 depletion (Fig. 2G)."