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CTNNB1 phosphorylates CTNNB1 on threonine. 3 / 3
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"In the absence of Wnt ligand, Axin contributes to the formation of beta-catenin destruction complex, which leads to phosphorylation of beta-catenin on serine and threonine residues near its N-terminus providing beta-catenin a target for ubiquitination and rendering it to ubiquitin dependent proteasome mediated degradation [XREF_BIBR, XREF_BIBR, XREF_BIBR]."
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"In non tumor cells, cytoplasmic beta-catenin levels are kept low due to its binding to a protein complex called the beta-catenin destruction complex (containing the APC tumor suppressor, the scaffold [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The β-catenin destruction complex is composed of Axin, APC, CK1α and GSK3β, and is responsible for phosphorylating the N-terminal serine and threonine residues of β-catenin 9."
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