IndraLab

Statements

Pirfenidone inhibits NLRP3. 4 / 4
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"Li et al. discovered that pirfenidone could inhibit the activation of NLRP3 inflammasome, which may be promising therapeutic strategy for ARDS."
| PMC
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"42 In a mouse model of lipopolysaccharide-induced ALI, pirfenidone has been shown to reduce both inflammation and fibrosis by blocking the activation of the NLRP3 inflammasome."
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"In a mouse model of lipopolysaccharide-induced ALI, pirfenidone has been shown to reduce both inflammation and fibrosis by blocking the activation of the NLRP3 inflammasome."
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"Pirfenidone also blocks NLRP3 inflammasome activation, it ameliorates lipopolysaccharide induced inflammation and fibrosis."
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