IndraLab

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TWIST1 increases the amount of USP13. 3 / 3
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"Twist1 inhibits USP13 promoter transcription."
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"In addition, we found that the protein levels of Twist1 dose-dependently increased with USP13 overexpression, while USP13 knockdown resulted in a decreased expression of endogenous Twist1."
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"These results underscore a key role of Twist1 in a USP13-induced enhancement of migration and invasion capacities of breast cancer cells.We also assessed the effects of USP13 expression on lung metastasis of breast cancer to further substantiate the above in vitro findings."
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