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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SIRT1 deacetylates KCNMA1. 3 / 3

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"SIRT1 activation decreased BK channel acetylation (-8+/-5%, n = 5), but the difference was not significant (P = 0.24)."

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"BK channel deacetylation by SIRT1 in dentate gyrus regulates anxiety and response to stress."

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"SIRT1 inhibition significantly increased BK channel acetylation (post-hoc Dunnett 's multiple comparison; P < 0.01; 23.35 +/-3.6%, n = 5; Fig."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

SIRT1 deacetylates KCNMA1. 3 / 3

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