IndraLab

Statements

Tolterodine inhibits KCNH2. 4 / 4
1 | 3
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"The IC50 for hERG block (37 degrees C) by tolterodine was 9.6 nM and by terodiline was 375 nM, values near or below clinical concentrations."
17110801
tas
No evidence text available
15911273
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"Tolterodine block of HERG displayed a positive voltage dependence, suggesting an interaction with an activated state."
14711935
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"However, the molecular mechanism of hERG channel inhibition by tolterodine is largely unclear."
35881423