IndraLab

Statements

LY294002 inhibits RELA. 6 / 7
1 | 5
reach
"Of note, Gas6 dependent AKT activation was responsible for the nuclear translocation of the anti-apoptotic NF-kappaB subunit p65, since it was detected in nuclear extracts of LX2 cells immediately after rGas6 administration, while PI3K inhibitor LY294002 blocked p65 nuclear upregulation."
25908269
reach
"In the present study, NF-kappaB (p65) expression was decreased in the EC109 cells treated with metformin or LY294002, but increased in insulin treated EC109 cells pretreated with or without metformin."
29435022
reach
"Both LY294002 and parthenolide inhibited EGF induced nuclear accumulation of NF-kappaB p65."
23383347
reach
"Inhibition of PI3K and Akt signaling with LY294002 increased p65 in the nucleus in IL-lbeta+ IFNgamma -stimulated hepatocytes and reversed the dbcAMP induced suppression of nuclear p65 (XREF_FIG)."
20934465
ctd
No evidence text available
21173233
reach
"Furthermore, GMPH inhibited nuclear transcription factor kappa-B (NF-kappaB) activation by suppressing the nuclear translocation of NF-kappaB p65, which was markedly reversed by LY294002, an Akt inhibitor."
29666854