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USP1 activates CASP3. 1 / 1
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"In contrast, the activation of the EcRB1/USP1 transcription complex by 20E led to an upregulation of PKCδ expression in various tissues during metamorphosis, while silencing PKCδ hindered the larval–pupal transition, inhibited tissues from undergoing autophay and apoptosis, and resulted in a decreased expression of the transcription factor Brz-7, as well as the apoptotic executors caspase-3 and caspase-6 [105]."