IndraLab

Statements


JOSD2 activates FBN2. 4 / 4
| 4

reach
"These results collectively indicate that YAP/TAZ have critical roles in CCA proliferation and JOSD2 is a potential oncogenic DUB in YAP/TAZ-related CCA.3.2 JOSD2 promotes CCA cells proliferation and stabilizes YAP/TAZ proteins."

reach
"Depleting JOSD2 led to the degradation of YAP/TAZ and thereby significantly inhibited CCA proliferation both in vitro and in vivo."

reach
"The depletion of JOSD2 significantly impaired the proliferation of CCA cells."

reach
"The depletion of JOSD2 promoted YAP/TAZ proteasomal degradation and significantly impeded CCA proliferation in vitro and in vivo."