IndraLab

Statements


SNAI1 activates CYLD. 3 / 3
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"By curbing CYLD, Snail thus promotes both tumor growth and spread."
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"Now, Massoumi et al. show that Snail also promotes tumor cell division by shutting off the tumor suppressor CYLD."
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"Receptor-interacting protein kinase 1 (RIP1) was identified as a determinant of MEKi resistance via activation of the NF-κB pathway in melanoma cells, which mainly relied on the Snail1-mediated cylindromatosis (CYLD) process."